Research projects
Chemical and nutritional study of Unconventional Food Plants and Contextualization with Basic Education Students
In this project we are studying the nutritional and anti-nutritional potential, chemical profile and antioxidant activity of Eryngium foetidum, Maranta arundinacea, and Pilea microphylla (Unconventional food plants - UFP). In addition, the contextualization of UFP is carried out in theoretical/experimental subjects in Basic Education.
Chemical and biological studies of Croton antisyphiliticus Mart. (Euphorbiaceae)
Croton antisyphiliticus is a native shrub from the Cerrado biome, widely used by rural communities in the treatment of flu, as an antibiotic and against infections in general. After the ethnobotanical survey carried out by our research group in the Coqueiros community (Catalão - Goiás), this plant was selected for chemical study (isolation and characterization of the constituents of the ethanolic and aqueous extracts of the plant parts), as well as for biological evaluation (antioxidant, anti-inflammatory, antimicrobial, among others).
In silico development of molecular models of xanthones for the synthesis and isolation of Kielmeyera coriacea (Calophyllaceae) for the evaluation of antimicrobial and antiviral activity
Bioactive secondary metabolites present in species of the genus Kielmeyera justify their widespread use in folk medicine, especially in the treatment of diseases caused by virulent microorganisms. The popular knowledge mentioned in the ethnobotanical survey carried out in the Coqueiros Community integrated with the biological knowledge described for the genus Kielmeyera, we are planning the synthesis, as well as the isolation and chemical characterization, of xanthones present in the species K. coriacea Mart., popularly known as "pau-santo". For this, the development of active xanthone models employing artificial intelligence through the assessment of the Quantitative Structure-Activity Relationship (QSAR) have been carried out, as well as the synthesis and isolation of xanthones to tests against methicillin-resistant Staphylococcus aureus and the flaviviruses of Dengue, Chikungunya, Yellow Fever and Zika.
Study of the metabolomic profile of Saccharomyces cerevisiae and Pachysolen tannophilus co-culture to obtain xylitol
In this project, experimental planning with batch tests has been carried out to define the optimal proportion of yeasts and the most favorable operating conditions that maximize xylitol production. Furthermore, throughout the experiments, the metabolomic profile (primary and secondary) by CL-EM and molecular networking for identification of substances present in this process.
Chemical and biological studies of plants popularly used as an antiophidic
This research project aims to study the chemical profile and biological potential of Musa spp. and Mimosa gracilis spp. varieties which are used as antiophidic in the rural communities, aiming at a complementary alternative to serotherapy in the treatment of poisoning by snakes of the Bothrops and Crotalus genera.
Identification and agriculture application of molecules from secondary metabolism of Bacillus sp. and Serratia sp.
In the last few years the use of pesticides in the world has increased and Brazil occupies the first place in the world ranking, consuming 20% of what is sold worldwide. Therefore, the objective of this project is to optimize the process of extraction and application of bacterial extracts in the control of diseases in the rice culture, as well as to identify the molecules produced in their secondary metabolism, in order to insert another component in integrated management of rice culture.